D-Mannose, also known as Mannose is sugar just like glucose, in fact, it has the same chemical composition only different in 3D assembly.
Because of how identical it is to glucose, comes the greatest benefit of D-Mannose, it protects against Urinary Tract Infections (UTI) and might be even a good replacement for antibiotics in treating the most common UTI. Many consider it to be a natural cure for bladder infection.
The why of this, is that the bacteria that affect your urinary tract clings to glucose and to D-Mannose on the cell walls of your urinary tract causing the infection. When D-Mannose is given as a supplement and reaches your urinary tract, the bacteria cling to it instead and gets washed out with urine. This is especially effective in case of a urinary bladder infection which is known as cystitis.
Cystitis happens to be the most common UTI, and this is the main reason that D-Mannose would be of great benefit for treating it. The problem becomes even more severe when you know that 40% of all people affected with a UTI would suffer another episode within 6 months.
Are there any studies about D-Mannose and its effects?
This has been proven by several clinical trials in Europe and D-Mannose has been even been compared to the antibiotic nitrofurantoin, producing the same effects in treating UTI.
In one study from 2014 in the World Journal of Urology it was found that Mannose might prevent the reinfection that happens with at least 40% of the people suffering from a UTI.
In another study from 2016 performed at the Department of Gynecological Obstetrics and Urologic Sciences of “Sapienza” University of Rome, it was found that D-Mannose was effective in treating UTI and preventing subsequent attacks.
And in the meantime, The United Kingdom National Institute for Health Research is performing a double-blind study involving 508 women, half of which would have D-Mannose administered and the other half to receive placebo to correctly define the link between D-Mannose and UTI. This study would conclude in 2020.
What are the most common symptoms of UTI?
- Dysuria which is pain during urination.
- Urgency, which is the need to rush to urinate.
- Burning urination.
- Incontinence, which is the inability to hold the urination.
- A bad smell to the urine.
- Turbid or cloudy urine
- Pain in the pelvic area or the supra-pubic area.
- Fatigue, dizziness, and confusion.
Is D-Mannose of value outside of UTI?
Yes, in fact, the same can be said about some types of bacteria that might cause the lower intestine infection and the same happens when the bacteria clings to the D-Mannose to be pushed out as well.
D-Mannose is also considered a prebiotic which feeds and helps the health of the good bacteria in your intestine or gut which are known as probiotics and are also known as the microbiome of your gut.
The microbiome has several effects on your health, like protecting your heart, helping to stabilize your mood and protect you from cancer.
There is another role for D-Mannose for treating a rare condition of deficiency in glycoprotein production. The disorder is called congenital disorder of glycosylation or carbohydrate-deficient glycoprotein syndrome. This is a genetic disorder that some families have several members affected by it. This disease causes the person suffering from it to lose protein through the intestine, and D-Mannose has been proven to slow down this loss, in addition, it improves the functions of the liver and fixes the glucose profile and bleeding problems with people suffering from this disease.
In its own Mannose is supposed to be created in the body from glucose polymerization, but the supplementation of it is the way to fix the UTI by having it in excess and free from cellular bonding.
Where can you find Mannose in food?
It is abundant in several vegetables, legumes, and fruits, and they are:
- In vegetables: Mannose is high in green beans, cabbage, eggplant, turnip, green coffee beans, broccoli, shiitake mushrooms & kelp.
- Fruits: These fruits are rich in Mannose black currants, cranberries, red currants, gooseberries, cranberry juice, apples, peaches, tomatoes, oranges & blueberries.
- Beans and legumes: These beans and legumes are rich sources of Mannose, soybeans, lima beans, and kidney beans.
- Spices: Cayenne pepper is a rich source of Mannose even in its dried powdered form.
Are there any side effects to taking D-Mannose as a supplement?
The answer is there is almost no record of any major side effect, except in some cases where it caused some flatulence and bloating, other than that, D-Mannose is very well tolerated by oral intake.
Are there contraindications to using D-Mannose?
Well, there are no studies on pregnancy or breastfeeding, so, deal with it with care and consult your obstetrician before taking it.
If you are diabetic it is advised not to take D-Mannose supplements because it might cause your blood sugar profile to be harder to manage.
And lastly, if you have any kidney problems it is counter advised to use D-Mannose supplements.
Is there a recommended dosage for the intake of D-Mannose supplement?
Even though there are not a lot of studies to support an effective dosage, one study had suggested that 2 grams (1/2 teaspoon) of D-Mannose powder dissolved in a glass of water and taken every 3 hours for 2 weeks as a preventive measure of UTI recurrence.
To summarize the whole many health benefits of D-Mannose for people too busy to read all these information bits:
- D-Mannose is a sugar that might be good to treat and prevent UTI.
- D-Mannose is present in a lot of fruits and vegetables in nature.
- The side effects are minor like flatulence and being bloated.
- The recommended dosage is around 2 grams daily for 6 months.
- D-Mannose is readily present in the market as a supplement.
And this the whole deal with D-Mannose, may this information be of help to anybody suffering from chronic or recurrent UTI.
Important note: Please consult with your family doctor before taking any supplement, thank you.